The mRNA cancer vaccine's recent success has gone to a groundbreaking level as it has eliminated tumors in mice. Major development has sparked considerable hope for a universal treatment that will be effective in different cancer types.
University of Florida researchers made the revolutionary vaccine, which works by not only targeting specific tumor markers it also activates the body’s complete immune response.
Nature, Biomedical Engineering journal, published an extensive study demonstrating that the vaccine dose, particularly when combined with biopharmaceutical, reduces or completely destroys the tumors in models of bone, melanoma and brain cancers.
Dr. Elias Sayour, lead author in research, labelled the discovery as very unexpected, exciting and revealed: “The vaccine tricks the immune system into reacting as though fighting a viral infection, thereby attacking cancer cells.”
“We achieved these results not by directly attacking a specific tumor, but by revving up the immune system itself,” Co-author Dr. Duane Mitchell added.
The immunization shot was shown to revive sleeping T-cells and improve the presence of the PD-L1 protein, interpreting cancerous cells more vulnerable to immune response.
The milestone achievement in the health sector is built on prior work by the same research team featuring customized mRNA vaccines for glioblastoma, with similar technology use which was implemented in COVID-19 vaccines.
