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Oprah Winfrey becomes target of Ozempic conspiracy theories

Oprah Winfrey's looked thinner in latest videos as she arrived at an event

By The News Digital
March 06, 2026
Oprah Winfrey becomes target of Ozempic conspiracy theories

Conspiracy theorists are targeting Oprah, days after going after Jim Carrey and Demi Moore over their appearances. 

The American TV legend's appearance at a fashion show has sparked questions about her dramatic weight loss.

Demi Moore
Demi Moore 

Days after calling Demi Moore an "Ozympic victim", some users questioned whether Oprah too was using the drug for weight loss.

Notably, Oprah is known for openly discussing drugs like Ozempic/Wegovy.

Jim Carrey
Jim Carrey 

Ozempic (semaglutide) is primarily a medication approved for managing type 2 diabetes by controlling blood sugar levels, though it's widely used off-label for weight loss but there is no public evidence or confirmation that Demi Moore is diabetic.

The actress has historically attributed her physique to fitness, yoga, clean eating, and role preparation.