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Monday April 29, 2024

QAU scientists reveal genetic clues to lower COVID-19 contagion

Despite neighbouring countries and European nations facing higher mortality rates, Pakistan demonstrated resilience

By APP
March 16, 2024
A general view of the Quaid-Azam-University building. — APP/File
A general view of the Quaid-Azam-University building. — APP/File

Islamabad: Professor Dr. Amir Ali Abbasi and his team at the National Centre for Bioinformatics, Quaid-i-Azam University have uncovered the reasons behind Pakistan’s lower COVID-19 contagion rates in the pandemic’s initial phase (February to October 2020).

Despite neighbouring countries and European nations facing higher mortality rates, Pakistan demonstrated resilience. The research team conducted a detailed genetic investigation, analysing 203 genome samples of the COVID-19 virus in Pakistan.

Dr. Amir while talking to APP disclosed that random genetic changes, driven by the virus’s adaptability, significantly compromised its fitness, making it struggle against infected individuals'' immune systems. He suggested these genetic alterations contributed to a reduction in the coronavirus’s estimated virulence, easing the health burden.

Acknowledging complexity, Dr. Amir highlighted additional factors, including the genetics of the Pakistani population, efficient healthcare systems, and effective lockdown strategies, potentially influencing the reduced mortality rate.