Health

E-cigarettes raise concern for potential health risk

A systemic review reveals a new side to e-cigarettes

Published December 15, 2025
E-cigarettes raise concern for potential health risk
E-cigarettes raise concern for potential health risk 

E-cigarettes are not safe as people think.

In a recent systematic review and meta-analysis published in the journal BMC Public Health, researchers investigated the association between the use of electronic cigarette (e-cigarette) and the risk of myocardial infarction (MI aka heart attack) as well as stroke.

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For decades, cigarette smoking has been recognized as a major risk factor for coronary artery disease, hypertension, and stroke.

In response, the tobacco industry introduced electronic nicotine delivery systems (ENDS), commonly referred to as e-cigarettes or “vapes,” and promoted them as harm-reduction tools to aid smoking cessation.

The present study addressed this gap using a systematic review and meta-analysis (SRMA) conducted in accordance with the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

Conventional cigarette smoking was treated as a key confounder and subgroup variable.

Analysis showed that people who used e-cigarettes had 53% higher chances of MI compared with non-users.

Notably, among former cigarette smokers who currently use e-cigarettes, the odds of a heart attack were more than doubled.

These findings raise concerns about the cardiovascular safety of e-cigarettes and indicate that they should not be assumed to be risk-free alternatives, especially for cigarettes.

This systematic review suggested that e-cigarette use is associated with increased odds of myocardial infarction, particularly among individuals with a history of cigarette smoking.

Although exclusive vaping among never-smokers was not associated with statistically significant cardiovascular risk in this analysis, the elevated risk observed in former smokers raises concerns about the use of e-cigarettes as a harm-reduction tool.

Sadaf Naushad
Sadaf Naushad is a Journalist and Neurochemistry master's graduate with over four years of experience. Leveraging her scientific background, she specialises in celebrity wellness, mental health, and the psychology of lifestyle trends, bridging the gap between science and pop culture to provide expert insight into global icons' well-being.
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