Saturday September 25, 2021

No need for a vaccine third jab booster: study

Some countries have started offering extra doses, causing WHO to call for a moratorium on third jabs
AFP
September 13, 2021
An elderly patient receives the 3rd dose of the Pfizer-BioNtech Covid-19 vaccine in Paris, on September 13, 2021. — AFP
An elderly patient receives the 3rd dose of the Pfizer-BioNtech Covid-19 vaccine in Paris, on September 13, 2021. — AFP

Vaccines are effective enough at preventing severe COVID-19 that there is no current need for the general population to be given third doses, according to a report in The Lancet published Monday.

Some countries have started offering extra doses over fears about the much more contagious Delta variant, causing the World Health Organization to call for a moratorium on third jabs amid concerns about vaccine supplies to poorer nations, where millions have yet to receive their first jab.

But a report by scientists, including from the WHO, concluded that even with the threat of Delta, "booster doses for the general population are not appropriate at this stage in the pandemic".

The authors, who reviewed observational studies and clinical trials, found that vaccines remain highly effective against severe symptoms of COVID-19, across all the main virus variants including Delta, although they had lower success in preventing asymptomatic disease.

"Taken as a whole, the currently available studies do not provide credible evidence of substantially declining protection against severe disease, which is the primary goal of vaccination," said lead author Ana-Maria Henao-Restrepo, of the WHO.

She said vaccine doses should be prioritised to people around the world still waiting for a jab.

"If vaccines are deployed where they would do the most good, they could hasten the end of the pandemic by inhibiting further evolution of variants," she added.

Countries like France have started distributing third jabs to the elderly and people with compromised immune systems, while Israel has gone further, offering children 12 and older a third dose five months after full vaccination.

The Lancet study concluded that the current variants had not developed sufficiently to escape the immune response provided by vaccines currently in use.

The authors argue that if new virus mutations did emerge that were able to evade this response, it would be better to deliver specially modified vaccine boosters aimed at newer variants, than those based on the existing vaccines.

WHO chief Tedros Adhanom Ghebreyesus has called on countries to avoid giving out extra COVID jabs until the end of the year.

The UN health agency has set a global target of seeing every country vaccinate at least 10 percent of its population by the end of this month, and at least 40 percent by the end of this year.

It wants to see at least 70 percent of the world´s population vaccinated by the middle of next year.

But Tedros complained that while almost all wealthy countries have hit the 10-percent mark, and more than 70 percent have reached 40 percent, "not a single low-income country has reached either target".